Methods Used by Pharmaceutical Companies to
Get the Results They Want from Clinical Trials
 ■Conduct
a trial of your drug against a treatment known to be inferior.
 ■Trial
your drugs against too low a dose of a competitor drug.
 ■Conduct
a trial of your drug against too high a dose of a competitor drug (making your
drug seem less toxic).
 ■Conduct
trials that are too small to show differences from competitor drugs.
 ■Use
multiple endpoints in the trial and select for publication only those that give
favourable results.
 ■Do
multi-centre trials and select for publication only those results from centres
that are favourable.
 ■Conduct
subgroup analyses and select for publication only those that are favourable.
 ■Present
results that are most likely to impress – for example, reduction in relative rather
than absolute risk.
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