From here:
Baxter International Inc. says that a blood product it was testing failed to slow mental decline or to preserve physical function in a major study of 390 patients with mild to moderate Alzheimer's disease.
The company says that people who received 18 months of infusions with its drug, Gammagard, fared no better than others given infusions of a dummy solution.
Gammagard is immune globulin, natural antibodies culled from donated blood. Researchers thought these antibodies might help remove amyloid, the sticky plaque that clogs patients' brains, sapping memory and ability to think.
People who designed this phase III trials should have ome clear proof of the concept why these antiodies could be useful against AD... Or not?
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