Wednesday, June 26, 2013

Targeted failure of the week. Post No 86.Brentuximab vedotin


A small clinical study treating elderly Hodgkin lymphoma patients with a combination of Seattle Genetics' (SGEN_) Adcetris and chemotherapy has been stopped temporarily due to reports of pancreatitis, a dangerous swelling of the pancreas, the company confirmed Tuesday.

The decision to suspend patient enrollment in the Adcetris study due to concerns about pancreatitis was made by researchers at Chicago's Northwestern University, which designed and is conducting the study. Seattle Genetics says none of its Adcetris studies have been halted for any toxicity reasons.

Yes, antibody-drug conjugate (ADC) being extremely "sexy" "magic bullet" fails... Was it expected for those who understand all this targeted bogus??? For sure! More failures to come!

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