Cancer vaccine developers have seen their fair share of disappointments, and failures have spurred some companies to test their treatments in smaller patient subpopulations. Now, researchers at the University of Connecticut are narrowing their focus even further as they gear up to trial personalized cancer vaccines.
Using genome sequencing to identify the differences between protein sequences--called epitopes--in healthy versus cancerous tissue, they'll start up an initial clinical study for ovarian cancer patients once they nab FDA approval. The team will sequence DNA from the tumors of 15 to 20 women with ovarian cancer, using that information to make a personalized vaccine for each woman.
Basically it means that cancer vaccines do not work... Surprised? I am not...
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