Global spending on medicines
is set to soar by as much as 30% from 2013 to 2018, and by the latter year
total expenditures will be nearly $1.3 trillion, according to new forecasts.
The world pharma market will
increase at a compound average growth rate (CAGR) of 4%-7% during 2013-18,
rising $305-$335 billion over the period (based on constant exchange rates)
compared with $194 billion growth seen in the previous five-year period,
2009-13, when the CAGR was 5.2%, says the research, from the IMS Institute for
Healthcare Informatics.
This fast growth will be
driven primarily by increased specialty drug innovation, greater access to
medicines and reduced impact of patent expiries, says the study. It also
forecasts that annual spending growth will spike this year at $70 billion, up
from $44 billion in 2013 and $26 billion in 2012 and will moderate in the years
to 2018, although remaining at higher levels than those seen during 2009-13.
“The higher level of spending
growth we’re projecting over the next five years reflects an unusual
combination of higher spending on the surge of innovative medicines for
patients and lower savings from patent expiries,” says Murray Aitken, IMH
Health senior vice president and executive director of the IMS Institute.
“This is particularly evident
this year and next in developing countries, and especially in the US, which
accounts for more than a third of the global market,” he adds.
The developed markets – led by
the US, the five major European markets (France, Germany, Spain, UK and Italy)
and Japan – will be the primary drivers of this increased growth; while they
will moderate as cost-containment measures further limit price levels, rising
volumes will continue to contribute to overall market growth. Only France and
Spain will see a contraction in pharmaceutical spend per capita in 2018, as a
result of policies aimed at curbing spending growth.
The 21 “pharmerging” markets
which currently account for 25% of global medicines expenditures will increase
their spending by more than 50% by 2018, with a CAGR of 8%-11% over the
forecast period as they continue to broaden access to treatments due to their
expanding economies and ongoing government efforts to provide universal health
coverage. By 2018, over 80% of growth in the pharmerging markets will be
attributed to non-branded medicines, including greater use of biologic drugs.
China, which is already the
world’s second-largest pharmaceutical market, will reach spending levels of
$155-$185 billion in 2018, the report adds.
Specialty medicines are
expected to contribute 40% of total global spending growth to 2018, with higher
expenditures particularly in the developed markets. Much of this growth will be
from products which bring patients new treatment options, with particularly
notable advances expected in the areas of oncology, autoimmune, respiratory,
antiviral and immunosuppressant therapies.
The recent surge in cancer
drug innovation will continue and contribute to global spending on all oncology
drugs, which is set to rise from $65 billion in 2013 to around $100 billion in
2018, while the introduction and uptake of potent new hepatitis C therapies are
forecast to producing spending totalling about $100 billion in the five years
to 2018, the report forecasts.
Moreover, almost 200 new drugs
are expected to be launched in the next five years. Over 2,000 products are
currently in late-stage development, a quarter of which are oncology drugs.
However, the IMS Institute notes that the availability of new medicines to patients
worldwide varies significantly by country and disease area and that, on
average, fewer than half the medicines launched during the previous five years
are now available across the major developed markets.
- The IMS Institute points out
that its estimates are measured at ex-manufacturer level and do not factor in a
range of rebates, discounts, taxes and other adjustments that affect the net
amount received by manufacturers. The impact of these factors is estimated to
reduce growth by $60-$80 billion, or around 25% of the increase forecast, over
the next five years, it says
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