A new life for the failed approach?

So far so-called nanotechnology was not effective in development of novel medicines against cancer despite a huge expectation from scientific society. My last critical remarks are in this link. And do you know what? Now it is time for antibiotics! Exactly the same approach, exactly the same mantra:

Highly-targeted nanoparticles that deliver huge doses of existing antibiotics could be used to overload the defenses of drug-resistant bacteria, researchers from Brigham and Women's Hospital and MIT reported in the journal ACS Nano.

 

The scientists have been working towards this goal by developing a nanoparticle that invades the immune system, targeting the infection sites, and subsequently release a focused antibiotic attack. 


The new nanoparticles were created from a polymer capped with polyethylene glycol (PEG), which is commonly used for drug delivery due to its nontoxic properties and because it can help to transport nanoparticles through the bloodstream without being detected by the immune system. 

The researchers then induced the particles to specifically target bacteria.

 

The nanoparticles start releasing their drug payload, which is embedded in the particle's core, once they bind to bacteria. The researchers designed the particles to deliver vancomycin, which is used to treat drug-resistant infections, However, it is possible to modify the particles to deliver other antibiotics or combinations of drugs. With increasing acidity, many antibiotics tend to lose their efficacy. However, the team discovered that antibiotics carried by nanoparticles retained their potency better than traditional antibiotics. 

The current version of nanoparticles discharges its drug payload over one to two days.

I would like to wish them to be successful and develop a novel medicine, however I am a little bit skeptical regarding this approach: why should it work against bacteria if it completely failed in oncology?