Very interesting article (pdf is here).
If we forget a lot of BS regarding targeted drugs mentioned in the
article we can come to the final message of the article:
All these
seemingly unrelated facts finally make sense by postulating that not
only does ionizing radiation produce apoptosis through ROS but also
today’s most effective anti-cancer chemotherapeutic agents as well
as the most efficient frame-shifting mutagens induce apoptosis
through generating the synthesis of ROS.
Well, in other words, drugs generate
ROS and ROS induce apoptosis. Regardless of ”targeting”.
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