Boehringer was
granted priority review for its epidermal growth factor receptor
(EGFR) inhibitor afatinib in NSCLC patients with locally advanced or
metastatic disease who test positive for the EGFR mutation.
Between 10 and 25
per cent of Caucasian NSCLC patients are EGFR-positive, with the
proportion rising to 30-40 per cent in some Asian populations.
Meanwhile, Roche
and Astellas have been given a fast-track review for their EGFR
inhibitor Tarceva (erlotinib) in first-line NSCLC, an indication for
which it was approved in Europe in 2011. Once again approval is being
sought to use the drug in patents with locally advanced or metastatic
NSCLC who are EGFR-positive.
Well, what about
the rest (majority) of the NSCLC which is not EGFR-positive???
No comments:
Post a Comment