Monday, April 2, 2012

Cancer vaccine does fail...


From Wikipedia:
Sipuleucel-T (APC8015, trade name Provenge), manufactured by Dendreon Corporation, is a therapeutic cancer vaccine for prostate cancer (CaP). It must be prepared specifically for each patient. In metastatic prostate cancer, it has extended survival by about four months. It costs $93,000 for a course of treatment.

The novelty of approach and intuitive understanding of the mechanism behind the treatment (keyword “vaccine”) would imply that we have here a possibility for a Black Swan! The cost of treatment can also convince us that the treatment is very complex, even very complicated.

 Well, the results of clinical trials were not so encouraging but there is still a chance to have a Grey Swan situation here. However I am afraid that the situation is transforming to becoming a Dirty Swan. According to this article Provenge has a lot of trouble. It is disappointing that this novel approach seems to fail. We need more new creative ideas!

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